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AIEX purification parameters for phosphorothioate oligonucleotides

Introduction Oligonucleotides with a phosphorothioate backbone Oligonucleotide (ON)-based therapeutics is an evergrowing market with an increasing number of both FDA approved ON drugs and clinical...
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Properties of WorkBeads 40 IEX resins: What makes them exceptional?

Chromatography agarose resins Agarose-based chromatography resins consisting of highly cross-linked porous beads have been used for decades to purify and separate a diverse set of macromolecules....
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Purification of oligonucleotides by anion exchange chromatography

Solid-phase synthesis of oligonucleotides generally give material of rather high purity. However, for many applications, and especially for therapeutics, there is a need for purification to remove...
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Platform for mAb purifications

Therapies based on monoclonal antibodies (mAbs) currently represent the largest and fastest developing biopharmaceutical market. The need for efficient mAb purification platforms is therefore...
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