Optimizing your IMAC purification
Results from IMAC purifications depend both on the chelated metal ion and the chelator itself Immobilized Metal Ion Affinity Chromatography (IMAC) utilizes the affinity of histidine, cysteine and...
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Addressing the challenge of optimizing His-tagged protein purifications
Introduction Immobilized Metal Affinity Chromatography (IMAC) is the commonest technique for purification of His-tagged proteins. Tagging proteins enables the use of affinity chromatography for...
Easy optimization of His-tagged protein purification
Introduction Immobilized Metal Ion Affinity Chromatography (IMAC) utilizes the affinity of histidine, cysteine and tryptophan on the protein surface for binding to metal ions immobilized on the...
Improved key quality attributes of antibody purification processes
Introduction The rapidly growing monoclonal antibody (mAb) market and the increasing demand for improved process economy put pressure on creating efficient downstream processing. WorkBeads™ affimAb...
Advantages of investing in a custom chromatography resin for your target molecule
When it comes to optimizing and refining your purification processes, nothing can surpass the precision and effectiveness of a custom chromatography resin. It is designed for your specific...
Optimized purification of antibodies using a new high-capacity and alkaline stable protein A resin
Introduction A new protein A chromatography resin has been designed for purification of mAbs, Gabs and polyclonal antibodies. The new resin, WorkBeads™ affimAb, is designed for high dynamic binding...
Efficient protection of protein A resins during mAb purifications
Introduction The purity requirements are high for monoclonal antibodies (mAbs). Using protein A chromatography resins result in mAbs with high yield and purity in a single step and is therefore the...
A novel protein A-based resin for optimized purification of antibodies
Introduction A protein A ligand designed to give high alkaline stability was immobilized on WorkBeads™ basematrix. The combination of ligand concentration and resin properties was optimized for high...
Improving your mAb purification
An expanding mAb market drives the need for high-efficient protein A resins Monoclonal antibodies (mAbs) are genetically identical antibody copies used primarily in therapy and diagnostics. The main...
Platform for mAb purifications
Therapies based on monoclonal antibodies (mAbs) currently represent the largest and fastest developing biopharmaceutical market. The need for efficient mAb purification platforms is therefore...