Blog

Trends and know-how in biotech and downstream purification.

A novel protein A-based resin for optimized purification of antibodies

Introduction A protein A ligand designed to give high alkaline stability was immobilized on WorkBeads™ basematrix. The combination of ligand concentration and resin properties was optimized for high...

Improving your mAb purification

An expanding mAb market drives the need for high-efficient protein A resins Monoclonal antibodies (mAbs) are genetically identical antibody copies used primarily in therapy and diagnostics. The main...

Platform for mAb purifications

Therapies based on monoclonal antibodies (mAbs) currently represent the largest and fastest developing biopharmaceutical market. The need for efficient mAb purification platforms is therefore...

Protection of protein A resins during mAb purifications

Today, monoclonal antibodies (mAbs) represent the largest and most progressive biopharmaceutical market. The mAbs used for clinical applications are subject to very high purity requirements and there...

How diversity in peptide therapeutics can revolutionize medicine

More than 80 peptide drugs have been approved by the FDA so far, and many more are in clinical development for a wide range of diseases. Peptide drugs have substantial therapeutic potential because...

Hydrophobic Interaction Chromatography: Understanding its principle and usage

Discover the fascinating principle behind hydrophobic interaction chromatography and how it is used in scientific research and analysis to separate biomolecules based on their hydrophobic properties.

Traditional Chinese medicine: Separation techniques that improve efficacy

Traditional Chinese medicine (TCM) is an ancient traditional medical system that has developed over thousands of years in China without recorded external influence. TCM includes various treatment...

Current trends in Advanced Therapeutic Medicinal Products (ATMPs)

Advanced therapy medicinal products (ATMPs) are human therapeutics that are based on genes, tissues or cells. They offer groundbreaking new opportunities for the treatment of disease. In many ways,...

How to improve peptide purification for affordable insulin

The global diabetes pandemic has created a massive demand for insulin, especially in China, which is expected to have half the world’s diabetes patients soon. Meeting this demand means developing...

How reversing downstream bioprocess steps can make all the difference

Improving the downstream bioprocess economy depends on fine-tuning an enormous range of parameters, from culture and harvesting to purification and final polishing. Success depends on the ability to...