Blog

Trends and know-how in biotech and downstream purification.

Easy optimization of His-tagged protein purification

Introduction Immobilized Metal Ion Affinity Chromatography (IMAC) utilizes the affinity of histidine, cysteine and tryptophan on the protein surface for binding to metal ions immobilized on the...

Improved key quality attributes of antibody purification processes

Introduction The rapidly growing monoclonal antibody (mAb) market and the increasing demand for improved process economy put pressure on creating efficient downstream processing. WorkBeads™ affimAb...

Advantages of investing in a custom chromatography resin for your target molecule

When it comes to optimizing and refining your purification processes, nothing can surpass the precision and effectiveness of a custom chromatography resin. It is designed for your specific...

Optimized purification of antibodies using a new high-capacity and alkaline stable protein A resin

Introduction A new protein A chromatography resin has been designed for purification of mAbs, Gabs and polyclonal antibodies. The new resin, WorkBeads™ affimAb, is designed for high dynamic binding...

Efficient protection of protein A resins during mAb purifications

Introduction The purity requirements are high for monoclonal antibodies (mAbs). Using protein A chromatography resins result in mAbs with high yield and purity in a single step and is therefore the...

A novel protein A-based resin for optimized purification of antibodies

Introduction A protein A ligand designed to give high alkaline stability was immobilized on WorkBeads™ basematrix. The combination of ligand concentration and resin properties was optimized for high...

Improving your mAb purification

An expanding mAb market drives the need for high-efficient protein A resins Monoclonal antibodies (mAbs) are genetically identical antibody copies used primarily in therapy and diagnostics. The main...

Platform for mAb purifications

Therapies based on monoclonal antibodies (mAbs) currently represent the largest and fastest developing biopharmaceutical market. The need for efficient mAb purification platforms is therefore...

Protection of protein A resins during mAb purifications

Today, monoclonal antibodies (mAbs) represent the largest and most progressive biopharmaceutical market. The mAbs used for clinical applications are subject to very high purity requirements and there...

How diversity in peptide therapeutics can revolutionize medicine

More than 80 peptide drugs have been approved by the FDA so far, and many more are in clinical development for a wide range of diseases. Peptide drugs have substantial therapeutic potential because...